Oakes Lab

Protein Folding Disorders [PFD]


a class of over 100 human diseases caused by the misfolding, aggregation, and accumulation of protein in specific cells leading to their dysfunction. The list of PFD includes diabetes, retinitis pigmentosa, amyotrophic lateral sclerosis, Alzheimer’s, Parkinson’s, certain cancers, and many others which in total affect hundreds of millions of individuals worldwide.